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Inherited mutations in the gene BRCA2 significantly increase the risk of carriers to breast and ovarian cancers. BRCA2, a crucial player in the body's DNA repair system, aids in repairing damaged DNA.

Real-world treatment patterns and outcomes of zanubrutinib in chronic lymphocytic leukemia and small lymphocytic leukemia (CLL/SLL). This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting ...

AI has fundamentally altered the feasibility of natural product discovery from fungal endophytes. Advances in genome sequencing, metabolomics, and systems biology have generated vast datasets, but ...

The field of cancer research has increasingly focused on the metabolic underpinnings of tumorigenesis, recognizing how the reprogramming of cellular energy ...

The Horner–Wadsworth–Emmons (HWE) reaction is a fundamental reaction in organic chemistry, widely used to create conjugated carbonyl compounds. Conjugated carbonyl compounds are used in many ...

Anticancer drug discovery has evolved into a multidisciplinary endeavour that integrates medicinal chemistry, biological evaluation and in silico studies to design agents with enhanced efficacy and ...

The National Institutes of Health (NIH) Center for Scientific Review has appointed Sukyung Woo, PhD, associate professor, Department of Pharmaceutical Sciences, to serve as a member of its Drug ...

(Top) Melanoma develops resistance to BRAF inhibitors, leading to cancer recurrence. (Bottom) By combining polyamine biosynthesis inhibition with BRAF inhibitors, the recurrence of cancer can be ...

Last year, obesity treatment drug sales surpassed the immune anticancer drug ‘Kitruda,’ which had long held the top sales position. On the 8th, Eugene Investment & Securities estimated this in a ...