An interview with Dr. Michael Dong, about his upcoming talk at Pittcon. Why are stability-indicating methods important in pharmaceutical analysis? The stability-indicating assay is perhaps the single ...

The use of acidic MPAs (pH 2–4) is the default in pharmaceutical testing because they suppress silanol ionization (from Si-OH to Si-O -) and improve peak shape for basic drugs. However, highly ...

Many people use high performance liquid chromatography, yet very few understand how they work. HPLC seems like a complicated combination of motors, gears, pressures, flows, chemistry, physics and ...

Since biological therapeutics are derived from living organisms, their manufacture and validation presents difficulties not encountered during traditional small molecule drug development. Despite the ...

When conducting reproducible and interference-free analysis by liquid chromatography, the purity of the solvents used, particularly the purity of water, is crucial for the sensitivity of this method, ...

What will you learn on this course? Module 9 of the Complete LC & LC-MS and part 1 of The LC & LC-MS Clinic courses. This module examines the method development process in detail; covering the ...