Autoimmune disease occurs from the body’s immune system attacking its healthy cells. Unfortunately, the mechanism that would normally prevent autoimmunity is not present in some individuals. T cells ...

Autoimmune diseases arise when the immune system mistakenly targets and damages the body’s cells and tissues as though they were foreign invaders. This widespread category of illnesses, such as ...

More than two decades ago, a research team discovered a type of T cell in humans that suppresses the immune system; they later found that these so-called regulatory T cells, when defective, are an ...

Northwestern Medicine scientists in the laboratory of Stephen Miller, Ph.D., professor emeritus of Microbiology–Immunology, have identified the cellular and molecular mechanisms required for the ...

The immune system’s capacity to distinguish self from non-self is in large part mediated by immunoglobulins, with IgG playing a pivotal role in both protective and pathological responses.

July 2, 2010 — Alopecia areata (AA), a hair-loss disease often considered similar to psoriasis because of the inflammation and T-cell involvement, shares many genetic associations with a broad ...

In healthy people, binding of the molecule acetylcholine (ACh) to its receptor (AChR) on skeletal muscle cells triggers muscle contraction underlying regular daily activities. In the autoimmune ...

Multiple sclerosis (MS) is a chronic autoimmune disease caused by the interaction between environmental factors, such as high dietary salt intake, and genetic risk factors. When regulatory T cells, ...

The first keynote presentation of this week's Keystone meeting on autoimmunity and transplantation tolerance ended in a rather surprising way -- the speaker was actually heckled during the question ...