Figure 1: Cartoon structures of the I·C and I·A base pairs. The increased width of the purine-purine I·A base pair requires the geometry of the anticodon to change, as the codon base is held in place ...
During normal translation, the binding of a release factor to one of the three stop codons (UGA, UAA or UAG) results in the termination of protein synthesis. However, modification of the initial ...