Two Bayesian clinical trial designs that perform subgroup-specific decision making and inference based on elicited utilities of patient outcomes are reviewed. The first is a randomized comparative ...
We review Bayesian and Bayesian decision theoretic approaches to subgroup analysis and applications to subgroup-based adaptive clinical trial designs. Subgroup analysis refers to inference about ...
What physicians should know about FDA's new proposed guidance ...
The Annals of Statistics, Vol. 48, No. 4 (August 2020), pp. 2277-2302 (26 pages) Motivated by problems in data clustering, we establish general conditions under which families of nonparametric mixture ...