Kidney damage is a serious complication affecting individuals with lupus, an autoimmune disease where immune B cells ...

Yale researchers have identified CD8+ T cells as a key driver of kidney damage in lupus, challenging the long-standing focus on B cells. The discovery may explain why some patients do not respond to ...

T-cell profiles derived from blood and renal biopsy may be novel biomarkers of lupus nephritis treatment response, study findings suggest.

Rutgers University researchers find that certain aging immune T cells can blunt cell expansion and may help explain why many ...

Children's Hospital of Philadelphia Pathology and Laboratory Medicine researchers uncovered how killer T cells – called CD8+ T cells – keep fighting inside tumors, where nutrients are scarce and ...

Researchers at the Max Delbrück Center and the University of Oxford have found that a cellular housekeeping function called autophagy—by which cell components are broken down and recycled—plays a ...

Meet the Jekyll and Hyde of the immune system: activated CD8⁺ T cells. On June 24 in Nature Immunology, researchers led by Dorian McGavern at the National Institutes of Health introduce a granzyme ...

During infection or cancer, cytotoxic T lymphocytes attach to their target and establish an exchange zone known as the immune ...

Like the surface of the moon, new research published today in Cell finds the existence of craters on the surface of melanoma cells that serve as immune hubs, becoming major sites for tumor killing.