Praxis Precision Medicines' ulixacaltamide (PRAX-944) is a potent and selective small molecule T-type Ca2+ channel blocker being developed for the potential treatment of essential tremor. ET is a ...

Myotonic dystrophy is one of the most common forms of muscular dystrophy. It is a genetic condition that causes progressive muscle weakness and wasting. No treatments currently exist that slow the ...

Antihypertensive drugs are associated with an increased risk for eczematous dermatitis in older adults, and the effect sizes are largest for diuretics and calcium channel blockers, according to a ...

Please provide your email address to receive an email when new articles are posted on . Beta-blockers more effectively reduce risk for death or hospitalization in people with HFpEF compared with ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Use of calcium channel blockers (CCBs), particularly cardioselective agents, had a modest but statistically significant association with glaucoma, a large meta-analysis showed. Overall, patients with ...

Little additional work has been performed beyond that of Lee et al. [1,3,10] to further investigate the proposed dual action of ibutilide. Our laboratory has sought to examine the effects of sodium ...

Many medications can help lower high blood pressure (hypertension), but no single one works best for everyone. The good news is, with some patience and help from your healthcare provider, you’ll ...

Blocking calcium channels in brain capillaries may enhance blood flow and alleviate early-stage Alzheimer's damage, new study suggests. Study: Inhibiting Ca 2+ channels in Alzheimer’s disease model ...

The researchers looked at 13 different studies and found that several kinds of drugs used to lower blood pressure may increase the chance of getting psoriasis. These drugs include ACE inhibitors, beta ...