This finding, he suggests, helps link the study of cell death in the worm and oncogenesis in people. "There were a number of papers that had suggested a relationship between cell death and oncogenesis ...

Cells that are about to die send a signal to an executioner protein, but sometimes, those cells can fight back and regenerate ...

Metacaspases, ancestral homologues of the caspase family, are pivotal cysteine proteases found in a wide range of unicellular organisms, including yeasts, algae, and phytoplankton. These enzymes ...

When tissue is severely damaged, surviving cells can respond in a concentrated burst of biological repair known as ...

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease. Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn's disease, ...

A team of researchers at the University of Cologne’s Center for Biochemistry, together with the Bambino Gesù Pediatric Hospital in Rome, Italy, have discovered a fundamental biological mechanism that ...

Discover the challenges of acute myeloid leukaemia linked to inflammatory cell death and the quest for effective therapies.

In an extensive review, researchers explore ZBP1-mediated programmed cell death and its potential as a therapeutic target for systemic diseases Programmed cell death, or PCD, is an actively regulated ...

A recent study links chemotherapy to impaired ovarian function and fertility through oxidative damage to ovarian follicles.

Scientific consensus on the biological mechanisms underpinning sunburn has remained largely unchanged for decades. The ...