Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

Every second, hundreds to thousands of molecules move through thousands of nuclear pores in each of your cells. A new high-definition view reveals the machine in action.

Using advanced microscopy techniques and computational modeling, researchers have discovered how herpesvirus infection affects the host-cell nucleus. Researchers at the University of Jyväskylä ...

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden. The ...

Herpes simplex virus partially liquifies the tightly packed, gel-like interior of human cell nuclei to copy itself faster, a ...

Ongoing research aims to confirm the mechanism by which ICP4 fluidizes the nucleus, which could indicate specific targets to counter viral replication.

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...

Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought. Having the pacemaker ...

The origin of the nucleus remains hotly debated among scientists, but new imaging and genomic data are shedding light on this billion-year-old mystery.