1don MSN
The shape of things to come: How spheroid geometry guides multicellular orbiting and invasion
As organisms develop from embryos, groups of cells migrate and reshape themselves to form all manner of complex tissues.
The mechanical properties of tissue matrix are crucial for maintaining cell health and function. With aging, tissue matrix loses its mechanical integrity and exhibits altered biophysical properties, ...
Biofilms, ubiquitous bacterial communities embedded in a slimy matrix, are the oldest form of multicellularity on earth; they are extremely resistant to antibiotics and stick tenaciously to most ...
Single-cell analyses have emerged as powerful tools for studying cellular heterogeneity and gene regulation. Single-cell chromatin accessibility sequencing (scCAS) is a key technology that enables the ...
AZoLifeSciences on MSN
Spheroid shape predicts cell invasion patterns in collagen matrix
As organisms develop from embryos, groups of cells migrate and reshape themselves to form all manner of complex tissues.
Research and drug discovery are undergoing a transformation, driven by the rise of 3D cell culture models that better replicate human biology. Unlike traditional 2D cultures and animal models, which ...
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