Fentanyl’s powerful pull comes from both the potent, rapid euphoria people feel while on the drug and the devastating symptoms of withdrawal. Researchers have now zeroed in on brain circuits ...

Fear memories can form in the brain following exposure to threatening situations such as natural disasters, accidents, or violence. When these memories become excessive or distorted, they can lead to ...

Scientists from Duke-NUS Medical School and the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) have discovered a novel pathway to wake up dormant neural stem cells, ...

Researchers at University of Tsukuba have identified a previously uncharacterized neural circuit that directly links emotional processing to arousal. In the pathway, GABAergic neurons in the bed ...

Neuroscientists find that two distinct neural pathways are responsible for the addictive properties of the opioid fentanyl: one mediates reward, the other promotes the seeking of relief from symptoms ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

Stress worsens sleep quality and can impair memory. Shinjae Chung, from the University of Pennsylvania, led a study to explore a neural pathway in male mice that stress may influence to cause sleep ...

Quick-acting targeted therapies with minimal side effects are an urgent need for the treatment of anxiety-related disorders. While delta opioid receptor (DOP) agonists have shown 'anxiolytic' or ...

Because unpleasant withdrawal symptoms fuel nicotine addiction’s high relapse rate, targeting their underlying mechanisms with treatments may promote continued abstinence from the drug. In a new ...

For the first time, scientists have generated a functional neural pathway for sensing pain in a dish. This could help unravel mechanisms of pain disorders. “This is important groundbreaking work,” ...