A new, epidemic strain of C. difficile is proving alarmingly deadly, and new research from the University of Virginia School of Medicine not only explains why but also suggests a way to stop it. Until ...

In a hamster model of Clostridium difficile, infection with C. difficile strains producing either toxin A or toxin B caused fulminant disease, according to a research team from the University of ...

PhD student Carrie A. Cowardin was working in the lab of Bill Petri, MD, PhD, chief of the University of Virginia’s Division of Infectious Diseases and International Health in Charlottesville, when ...

Affecting roughly half a million Americans each year, bacterial infections caused by Clostridioides difficile—commonly known as C. diff—are a serious and persistent problem for patients and hospitals ...

Future Microbiol. 2012;7(8):945-957. Patients infected with PCR ribotype 027 were found to have more severe diarrhea, higher mortality and more reoccurrences of symptoms. [44] It has been thought that ...

The presence of antigen-specific and neutralizing antibodies was not associated with Clostridioides difficile infection symptoms, severity, therapy approach, treatment response, or recurrences in a ...

A new, epidemic strain of C. difficile is proving alarmingly deadly, and new research not only explains why but also suggests a way to stop it. A new, epidemic strain of C. difficile is proving ...

Clostridiodes difficile infection has become a leading cause of severe, sometimes fatal diarrheal illness, with the bacterium's toxins causing the damage. New work cements our knowledge of how C. diff ...

Clostridium difficile infection is one of the most common healthcare-associated infections in adults in the United States. Older Americans are especially vulnerable to CDI, 2 and this infection has ...

BOSTON (Sept. 5, 2007) — As if being admitted to the hospital weren’t bad enough, patients, once admitted, are at higher risk of becoming infected with a “superbug” bacterium, Clostridium difficile (C ...

Researchers from the University of Maryland School of Medicine and their colleagues have identified the structure of the most lethal toxin produced by certain strains of Clostridium difficile bacteria ...

A new study, led by researchers from the University of California, Irvine (UCI), uncovers the long-sought-after, three-dimensional structure of a toxin primarily responsible for devastating ...