Rodent ClC-K1 and ClC-K2, and their respective human orthologs ClCKA and ClCKB, are chloride channels specific to the kidney (and inner ear); Barttin is their functionally important subunit. ClC-K1 is ...
Hypertension affects 1 billion people world-wide, contributing to 5 million deaths annually from myocardial infarction, stroke, kidney failure and heart failure. Its causes have been obscure owing to ...