Plasmid DNA (pDNA) is a fundamental starting material for therapeutic development, including for viral vectors, mRNA therapies, and DNA vaccines. Researchers use capture methods such as anion exchange ...

A new, robust method for protein elution from ceramic hydroxyapatite. Hydroxyapatite is used for the fractionation and purification of a wide variety of biological molecules. At commercial scale, the ...

IN several laboratories, where whole lipid extracts are chromatographed on silicic acid in chloroform-methanol, experience has suggested the need for continuous concave gradient elution. Devices are ...

Epitope tagging is a technique that employs genetic engineering to fuse a known epitope, called an affinity tag, to either the C or N terminus of a recombinant protein to facilitate affinity ...

Several chromatographic resins are available for downstream purification. Monoclonal antibodies (mAbs) are a successful class of therapeutic products used increasingly in the past 15-20 years, but the ...