The endothelial glycocalyx integrates mechanical signals with vascular biology, playing a vital role in health and disease, ...

A polygenic risk score (PRS) based on genes associated with endothelial cell function identifies patients at a higher risk of coronary artery disease, according to a new study. The risk score, which ...

In addition, Krüppel-like factor 2 (KLF2), a mechanosensitive transcription factor that regulates endothelial cell functions, was found to be upregulated. Taken together, their findings highlight the ...

BACKGROUND: Oscillatory shear stress (OSS), resulting from disturbed blood flow, is implicated in atherosclerotic plaque formation by incompletely understood mechanisms. This study aims to elucidate ...

A team led by the University of Sydney has identified red blood cell rupture at dying endothelial sites as a primary driver of microvascular obstruction in COVID-19, bypassing the expected role of ...

Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply ...