New research results are expanding our understanding of the physiological role of the glial cell line-derived neurotrophic factor GDNF in the function of the brain's dopamine systems. In a new article ...

Hoth Therapeutics, Inc. (NASDAQ: HOTH), a clinical-stage biopharmaceutical company, today announced positive data from its HT-VA study, conducted under its Cooperative Research and Development ...

Protection Against High-Fat Diet-Induced Obesity – GDNF-tg mice exhibited significantly lower body weight and reduced fat deposition despite consuming a high-fat diet. Enhanced Fat Burning and Energy ...

GDNF does not have a neuroprotective effect in this α-synuclein-induced toxicity model of PD In the paper by Decressac et al., 2 the authors questioned the relevance and predictability of toxin-based ...

The major goal of the research of Dr. Sidorova’s team in the Saarma lab is to develop neuroprotective and neuroregenerative drugs for disease-modifying treatment of nervous system disorders caused by ...

For the first time, researchers have witnessed dopaminergic neuron sprouting in a Parkinson disease (PD) patient treated with the neurotrophic factor GDNF. A postmortem examination of the brain of a ...

A new adenoviral vector (Ad-GFAP-GDNF) (Ad=adenovirus, GFAP=glial fibrillary acidic protein, GDNF=glial cell line-derived neurotrophic factor) was constructed in which (i) the E1,E3/E4 regions of Ad5 ...

A key factor in the motor symptoms associated with Parkinson’s disease is the gradual destruction of dopamine neurons. The glial cell-derived neurotrophic factor, or GDNF, has been proven to protect ...

Glial cell line-derived neurotrophic factor (GDNF) plays a vital role in promoting motor neuron survival and axon outgrowth. It is being evaluated in clinical trials as a potential therapeutic for ...

New research results are expanding our understanding of the physiological role of the glial cell line-derived neurotrophic factor GDNF in the function of the brain's dopamine systems. In an article ...