It's one of life's most defining moments - that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage ...
A serendipitous discovery in the lab has the potential to revolutionize embryo models and targeted drug therapies. Materials scientists at UNSW Sydney have shown that human pluripotent stem cells in a ...
A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilised egg, starts to develop, ...
Toward the goal of generating high-quality embryo models in vitro, this study establishes a stepwise protocol to derive trophectoderm-like cells from mouse extended pluripotent stem (EPS) cells. These ...
The distinct parental origins of the X chromosome lead to X-specific lower methylation in female embryos (at least in TE lineage), which, combined with the incomplete X chromosome inactivation and sex ...
Roger Sturmey receives research funding from UKRI, NC3Rs, Tommys, ESHRE, and British Heart Foundation. He serves as Chair of the Guideline Working Group for the "Governing Stem Cell-Based Embryo ...