Genetic defects are exceedingly common, which is not surprising considering just how many cells make up our bodies, including our reproductive cells. While most of these defects have no or only minor ...

Companies are adopting diverse approaches to reducing unwanted toxicities associated with cell and gene therapy.

An understanding of the origin and dynamics of heritable genetic variation within classical animal breeding programs is needed to provide the context for understanding the contributions and concerns ...

Genetic regulation of glucose homeostasis is central to the maintenance of human health and the prevention of metabolic disorders such as type 1 and type 2 diabetes. Recent advances in molecular ...

Knockdown of CUL5 gene enhances CAR-T cells’ prolification and survival compared to conventional CAR-T cells, making them better at fighting cancer. Researchers have identified a method to enhance the ...

A new platform identifies which genes drive particle assembly to engineer cells that yield more potent delivery vehicles.

Researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation. Researchers have determined ...

An ad hoc committee appointed by the National Academies to explore heritable genetic modifications of food animals. This committee will address methods for heritable genetic modifications and identify ...