Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to ...

Kahland, T., Lindenwald, D.L., Jeschke, M. et al. Generation of marmoset monkeys with a non-mosaic disruption of the OTOF gene as a model of human deafness. Nat Commun (2026).

Researchers unveiled an approach to drug discovery that could revolutionize how we understand and treat diseases. Their commentary explains the limitations of studies using traditional mouse models ...

Researchers develop a genetically modified mouse model to uncover the links between dendrite defects in osteocytes and impaired bone remodeling CHINA, August 12, 2025 ...