There is viral DNA in the human genome, and each instance traces back to an ancestor who was infected with a retrovirus. HIV might be the most well-known retrovirus, a microbe that can integrate its ...

Around 45 percent of human DNA is made up of transposable elements, or TEs—genetic leftovers from now-extinct viruses that scientists once believed to be “junk DNA.” But that view is changing, and a ...

Weill Cornell Medicine researchers have found that temporarily disabling a protein complex that organizes DNA into loops ...

Yes, we are. In fact, more than 4,300 different whole genomes have been sequenced, nearly 200 of which are eukaryotic. Moreover, with targeted exome resequencing included, many more thousands of ...

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., at UMass Chan Medical School, has extensively mapped and analyzed the three ...

The human genome is about two meters long, yet it fits inside a nucleus only ~10 micrometers in diameter. A research team led ...

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" ...

Four Northwestern scientists published a study in December as part of the 4D Nucleome Project, which maps the genome in 3D and illustrates how its structure changes over time. According to the study, ...

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional ...