Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into ...

A retrospective study highlights the potential for encephalitis and other serious neurologic side effects over the course of ...

Immune checkpoint blockade (ICB) has reshaped modern immunotherapy by unleashing antitumor immune responses through targeting inhibitory immune checkpoints ...

AT-108 induces powerful, personalized anti-cancer responses by forcing tumor cells to present their antigens to the immune ...

M Series A to advance MBX-116, a live bacterial product designed to improve immune checkpoint inhibitor response in advanced melanoma.

The immune checkpoint inhibitors market presents opportunities in next-gen therapies targeting new immune checkpoints, boosting treatment efficacy, especially for difficult-to-treat cancers. Growth is ...

Immunotherapy has transformed cancer treatment by helping the body’s immune system recognize and attack cancer cells more ...

Patients who develop myocarditis within the first month of receiving immune checkpoint inhibitor therapy are more likely to have MC fatality.

The tumor microenvironment (TME) is highly complex and dynamic, shaped by diverse immune and tumor cell interactions. CD markers and immune checkpoints provide complementary insights into these ...

Immune system activation and activity is regulated through stimulatory or inhibitory ligand-receptor interactions collectively termed immune checkpoints. 1 Stimulatory interactions give the immune ...