Integrin activation unbends the molecule either by ligand binding or by effects on the cytoplasmic domains which straightens and separates the legs of the molecule. This exposes activation epitopes ...

Atherosclerosis represents a chronic inflammatory disease characterized by the accumulation of lipid-laden macrophage foam cells within arterial ...

Researchers from The University of Osaka find that chronic liver congestion is linked to severe liver diseases through a specific signaling pathway in liver sinusoidal endothelial cells - key cells ...

Atherosclerosis, a disease characterized by the accumulation of lipids and inflammatory cells in the arterial wall, is a significant cause of cardiovascular events. A key process in atherosclerosis is ...