Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. These ...
Mitogen-Activated Protein Kinase (MAPK) signalling pathways represent a fundamental means by which cells translate extracellular stimuli into a wide array of intracellular responses, including ...
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MET signaling plays a critical protective role in acetaminophen-induced acute liver failure
A new study has found that MET (hepatocyte growth factor receptor) signaling plays a critical protective role in acetaminophen-induced acute liver failure (ALF). This pathway is shown to work as a ...
A preclinical study has reported that simultaneous inhibition of cyclin-dependent kinases 2 and 4/6 produced durable tumour ...
NOTE. P < .00357 represents statistical significance after the Bonferroni correction. Abbreviations: MAPK, mitogen-activated protein kinase; NA, unable to be calculated; NR, not reached; OS, overall ...
The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...
The serine/threonine kinase glycogen synthase kinase-3β (GSK-3β) plays a multifunctional role through its involvement in ...
New research from the University of St Andrews has discovered a crucial piece in the puzzle of how all animals with a ...
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