The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal of lymph nodes ...

TLSs are highly organized structures that typically appear as clusters of B-cells containing FDCs. These clusters are then surrounded by T-cells and HEVs as shown schematically in Figure 1. We ...

Tertiary lymphoid structures (TLS) are ectopic cellular hubs that coordinate immunity within patient tumors. TLS also correlate with improved prognosis and superior response to immunotherapy. While ...

Researchers developed bioengineered lymphatic tissue that replaced missing lymph nodes in mice, with potential to treat lymphedema.

Bilateral germ cell tumor of the testis (TGCT): Implications for a stem cell versus genetic origin of cancers. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does ...

A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a ...

A little-known tissue composed of a cluster of immune cells could offer novel insights into the development of neurological disorders. Meninges' immune system changes with age and neurodegeneration.

Explore the innovative concept of bioengineered lymph nodes as a promising solution for lymphedema after cancer surgery.

An earache can turn a happy, energetic child into a cranky, uncomfortable one in no time. It's a common struggle—5 out of 6 kids will have an ear infection by age 3, according to the National ...

Immune checkpoint inhibitor (ICI) therapy before surgery for hepatocellular carcinoma (HCC) may produce major pathological response in about one-third of the surgical patients. The clinical and ...