Nature

Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells

CD4 + T lymphocytes recognize antigenic peptides presented by major histocompatibility complex (MHC) class II molecules on the surface of antigen-presenting cells (APCs). These peptides are derived ...
Nature

Classical and non-classical MHC I molecule manipulation by human cytomegalovirus: so many targets—but how many arrows in the quiver?

Major mechanisms for the recognition of pathogens by immune cells have evolved to employ classical and non-classical major histocompatibility complex class I (MHC I) molecules. Classical MHC I ...