Abbreviations: IHC, immunohistochemistry; MMR-D, mismatch repair deficient; MMR-I, mismatch repair intact; FU, fluorouracil; LV, leucovorin. Analysis method = cases with agreement between genotyping ...

Microsatellite instability and loss of heterozygosity has been implicated in ovarian carcinogenesis. The reported frequency of microsatellite instability in human ovarian cancer varies significantly ...

Microsatellite instability (MSI)/mismatch repair (MMR) status is increasingly important in the management of patients with cancer to predict response to immune checkpoint inhibitors. We determined MSI ...

An overview of data presented at ESMO GI 2023 on combined botensilimab and balstilimab therapy in heavily pretreated patients with microsatellite stable metastatic colorectal cancer. John L. Marshall, ...

Dr Marshall describes the impacts of microsatellite stability and instability on metastatic colorectal cancer. John L. Marshall, MD: Every patient with colon cancer and every physician treating colon ...

Merck & Co. has tapped the artificial intelligence developer Owkin to help assemble a new slate of digital diagnostics for cancer testing. The collaboration will expand upon Owkin’s machine ...

One in every three people is expected to have cancer in their lifetime, making it a major health concern for mankind. A crucial indicator of the outcome of cancer is its tumor microsatellite ...