Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein ...

Researchers have developed smart nanoparticles that can seek out and destroy disease-causing proteins the body can’t normally eliminate. Unlike traditional drugs, these particles can reach ...

Biomedical engineers at Duke University have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing ...

Targeted protein degradation has opened up a new field of drug discovery with potential to treat previously 'undruggable' diseases. The work means new drugs can be much more accurately targeted at the ...

Undruggable targets typically refer to a class of therapeutic targets that are difficult to target through conventional methods or have not yet been targeted, but are of great clinical significance.

Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular ...

Scientists have developed a new nanoparticle-based strategy that could dramatically expand the range of disease-causing proteins that can be targeted by modern medicine. A newly released perspective i ...

A Purdue University team has discovered a new therapeutic target for triple-negative breast cancer. The research, led by Kyle ...