Researchers test state-of-the-art models on diverse RNA structures, opening doors for RNA-based therapies and drug design Ribonucleic acid (RNA) is one of life’s most versatile molecules, with roles ...

Chemical modifications occur on many types of biological molecules, including nucleic acids, proteins, sugars, and lipids. These modifications typically function as molecular switches. For example, ...

Predicted SARS-CoV-2 WT and mutant s2m secondary structures. Using RNAfold, the predicted minimum free energy secondary structure of the WT and mutant s2m RNA sequences substituted into the SARS-CoV-2 ...

Researchers have reported a fundamentally new approach to the structural investigation of RNA molecules. ROCK, as it is called, uses an RNA nanotechnological technique that allows it to assemble ...

Example of an RNA thermometer in the gene lpxP, identified in E. coli and conserved across various bacterial species. On the left, the OFF conformation. The Ribosome Binding Site (RBS, green) is ...

SANTA CRUZ, CA — Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or “ribozyme,” that carries out a fundamental reaction ...

Credit: Carnegie Mellon University When the gene is transcribed into RNA, the chain of repeats forms a hairpin loop —a tangled structure that functions like a sticky trap for essential proteins. These ...