VIENNA — Tirzepatide was associated with improvements in body weight and body composition, and with lower insulin doses, in the first-ever randomized controlled trial (RCT) of the drug in people with ...

Early clinical trials established the safety and feasibility of closed-loop insulin delivery, but the 2019 iDCL trial1 marked the first large, outpatient, randomised, controlled trial to show a ...

Thought LeadersAoife Hayes, Kevin O'Regan & Julie ScanlonClinical Trials Assitant, Operations Manager & Quality Assurance ManagerAtlantia Clinical Trials Food clinical trials may not be as familiar to ...

A clinical trial to test the effectiveness of a new, plant-based oral drug to treat type 2 diabetes has produced some promising results. The drug significantly improved blood glucose control and ...

ACHIEVE-3 randomized 1698 metformin-treated adults with inadequately controlled type 2 diabetes to once-daily orforglipron ...

HARMONIA trial will assess multi-system efficacy, safety and tolerability of z-basivarsen in DM1 -- 48-week trial will enroll approximately 150 ...

A novel GLP-1 receptor agonist (RA) pill called orforglipron leads to a larger reduction in blood sugar levels after a year ...

Adjunctive glucocorticoids may reduce mortality among patients with severe community-acquired pneumonia (CAP) in well-resourced settings. Whether these drugs are beneficial in low-resource settings ...

Brain-training exercises may reduce the risk of dementia if they involve speedy thinking, whereas exercises involving memorization or reasoning have no effect on dementia risk, a two-decade-long trial ...