Cyclophosphamide is widely used to treat severe manifestations of numerous autoimmune rheumatic diseases including systemic sclerosis. Based on recent data, immunological and inflammatory activation ...

Please provide your email address to receive an email when new articles are posted on . Injections yielded significant improvements in visual analog scale pain and Quick-DASH score, as well as skin ...

Ask the Experts - Respiratory Failure in Dermatomyositis I have a female patient with recently diagnosed Jo-1 antibody-positive dermatomyositis (skin rash, creatine phosphokinase [CPK] >3000 U/L, nail ...

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and sometimes fatal illness stiffens and scars tissue in organs like the lungs, ...

Please provide your email address to receive an email when new articles are posted on . Data from two large U.S. cohorts showed more than 30% of patients with SSc demonstrated an initial symptom other ...

Most people with scleroderma have autoantibodies. Several scleroderma-specific antibodies have been identified. These can help with diagnosis and give insight into the type of disease you may ...

From the Department of Medicine, Harvard Medical School, and the Medical Research Laboratories, Beth Israel Hospital. Select the format you want to export the citation of this publication.

Scleroderma on the face can cause symptoms that may affect your appearance, including the texture, discoloration, and elasticity of your skin. Medications, facial exercises, and dermatological ...

Scleroderma is an autoimmune condition that causes the skin to become tight and hard. This can change facial appearance, such as the mouth becoming smaller, and affect internal organs. With ...

Scleroderma is a rare autoimmune disease involving an overproduction of the protein collagen. Linear scleroderma usually begins as a streak of hardened, waxy, discolored skin on the forehead, an arm, ...