Selective 2′-hydroxyl acylation analyzed by primer extension (SHAPE) chemistries exploit small electrophilic reagents that react with 2′-hydroxyl groups to interrogate RNA structure at ...
Why do rose petals have rounded ends while their leaves are more pointed? Scientists have revealed that the shape of petals is controlled by a hidden map located within the plant's growing buds. Why ...
Many biological processes are RNA-mediated, but higher-order structures for most RNAs are unknown, which makes it difficult to understand how RNA structure governs function. Here we describe selective ...