In a single experiment, scientists can decipher the entire genomes of many patient samples, animal models, or cultured cells. To fully realize the potential to study biology at this unprecedented ...

Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...

The growing understanding that most diseases are related to cellular dysfunction and dysregulation has researchers probing single cells to uncover the molecular mechanisms that contribute to disease ...

Researchers discovered immune cell aggregates in the gut may signal blood vessel cells and fibroblasts to produce excess collagen, driving fibrosis in Crohn’s disease. The findings could guide ...

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast ...

Breast cancer remains one of the most prevalent and life-threatening forms of cancer, impacting millions worldwide. This malignancy's heterogeneity and complexity have long posed significant ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest ...