Genomic structural variants (SVs) involve the rearrangement of DNA sequences and have the potential to drive phenotypic changes across the tree of life. The discovery of structural variation dates ...
Assessments of DNA misrepair, and the resulting effects on the structural integrity of the genome, are critical for evaluating the safety of cell and gene therapy applications. Most genome editing ...
Discover how hidden complexities of the human genome are revealed by scientists from The Jackson Laboratory. Technological advancements are now allowing us to assemble continuous genomes with ...
Researchers at Baylor College of Medicine’s Dan L Duncan Comprehensive Cancer Center and Human Genome Sequencing Center investigated the extent to which forms of genetic variation called germline or ...
A substantial chromosomal inversion in the DG1 promoter upregulates its expression. It gives rise to a double-grain spikelet trait remarkably augmenting the grain number and yield in sorghum and ...
I am a Systems Biology and Bioinformatics doctoral trainee with Dr. William Bush, in the department of Population and Quantitative Health Sciences. Our lab focuses on understanding the functional ...
The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...
Researchers built the most comprehensive cucumber pangenome to date, uncovering nearly 172,000 structural variants that ...
Researchers at Baylor College of Medicine's Dan L Duncan Comprehensive Cancer Center and Human Genome Sequencing Center investigated the extent to which forms of genetic variation called germline or ...
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