SAN DIEGO, CA—Does the use of a primary composite endpoint help or harm when it comes to interpreting modern-day clinical trials? Do softer clinical endpoints, such as recurrent angina, restenosis, or ...

Clinical trials are well-controlled and designed experiments that aim to prove that an Investigational Medicinal Product (IMP) is effective. Clinical trial data is submitted to the national health ...

Noninferiority clinical trials have become a major tool for the evaluation of drugs, devices, biologics, and other medical treatments. Treatment with placebo or with a no-treatment control in a study ...

Data analytics identify the top-performing practices in our research communities. The CTSC facilitates the integration of research with health systems management as well as with the community. We aim ...

Drug development enterprise is struggling because of prohibitively high costs and slow progress. There is urgent need for adoption of novel adaptive designs to improve the efficiency and success of ...