Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumour growth.

This research provides a comprehensive analysis of deleterious mutations in pear (Pyrus spp.) during domestication, shedding ...

In mantle cell lymphoma (MCL), an aggressive form of B-cell non-Hodgkin lymphoma, TP53 mutations are known to affect patients’ prognosis—but questions remain. What does the heterogeneity of TP53 ...

Using sequencing instruments from multiple vendors, scientists from the University of Utah Health, the University of Washington, PacBio, and elsewhere have developed what they claim is the most ...

Using cortical organoids from individuals with autism, researchers tracked gene activity over development. Early ...

Study results indicate that mutation strength may shape both tumor–immune system interactions and immunotherapy response.

Figure 3. Docking of ADNP_Glu931Glyfs12 to the PTB protein. (A) The results of docking ADNP_Glu931Glyfs12 (light orange) to the PTB protein (PDB code 3DXC, navy blue) in the 934-941 amino acid region ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth. The study focused on CTNNB1, a gene that produces the protein β-catenin, ...

A graph-based computational tool for detecting previously invisible genetic mutations has been developed. Researchers at the University of California, Los Angeles (UCLA; USA) and the University of ...