Multicellularity is one of the most profound phenomena in biology, and relies on the ability of a single cell to reorganize itself into a complex organism. It underpins the diversity in the animal ...

Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...

Magdalena (Magda) Zernicka-Goetz, today a developmental and stem cell biologist at the University of Cambridge and California Institute of Technology, recalled being an artistic child who enjoyed ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilised egg, starts to develop, ...

A collaboration between research groups at the University of California, TU Dresden in Germany and Cedars-Sinai Guerin Children’s in Los Angeles has identified a mechanism by which embryonic cells ...

Explore the intricate relationship between ovarian reserve, egg quality, and reproductive aging. Discover how mitochondrial ...

A recent Nature study evaluates post-implantation development in humans using embryo-like models based on genetically unmodified human naïve embryonic stem cells (ESCs). Study: Complete human day 14 ...

Though more than 8 million babies have been born through in vitro fertilization (IVF), 70% of IVF implantations fail. As IVF is becoming a more common route to pregnancy in cases of infertility, there ...

Some newly reported clumps of cells growing in lab dishes have been hailed as the closest things to human embryos that scientists have ever made in the lab. These entities are human embryo models — ...

Why doesn’t a ‘good’ embryo always lead to pregnancy in IVF? Explore key factors beyond embryo quality that affect IVF success explained by expert.