Scientists have found an explanation for how NAD affects the aging process. Johner Images/Getty Images Nicotinamide adenine dinucleotide (NAD) is a molecule found in every living cell of the body.

For years, researchers have watched the tiny power plants inside brain cells falter in Parkinson’s disease and wondered what came first. Did those damaged mitochondria trigger the illness, or did they ...

A study identifies PCBP1 as a regulator of AARS2 function in heart cells, linking its loss to mitochondrial damage, and ...

Serious damage to short-term kidney function—known as acute kidney injury, or AKI—can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

CRISPR-based gene editing has revolutionized modern biology, but these tools are unable to access the DNA that resides inside mitochondria. Researchers are eager to access and edit this DNA to ...

Sometimes I read a paper that literally gives me goosebumps—not because it gave me the answer to a question I’ve been seeking ...

Rooted in malfunctions in the tiny power plants that energize our cells, mitochondrial disorders are notoriously complex and variable, with few effective treatments. Now, novel findings in microscopic ...

Researchers have unveiled a new biological platform for studying mitochondrial DNA in physiology, adaptation, disease mechanisms, and therapeutic development.

EPFL scientists have discovered that a simple shape change in mitochondria helps cells evenly distribute their mitochondrial DNA, solving a long-standing puzzle. Subscribe to our newsletter for the ...