Major hurdles in early-stage drug discovery include how to triage hit compounds identified from cell-based screens, as well as how to rapidly evaluate their cellular efficacy and pinpoint side effects ...

miRNAs are short, noncoding RNA molecules, 16–29 nucleotides long, that modulate gene expression by base-pairing with the 3′ untranslated region of their target mRNAs. Depending on the degree of ...