Comprehensive map reveals how E3 ligases organize protein cleanup in human cells

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...
IEEE

Real-Time Shape Estimation of Tensegrity Structures Using Strut Inclination Angles

Abstract: Tensegrity structures are becoming widely used in robotics, such as continuously bending soft manipulators and mobile robots to explore unknown and uneven environments dynamically.
IEEE

Multi-Objective Structure-Based Drug Design Using Causal Discovery

Abstract: Structure-based drug design (SBDD) is a critical subtask in the drug discovery process, with deep generative models playing a pivotal role. Inherently, drug design is a multi-objective task ...
BMJ

Occupational risk of Parkinson’s disease and employment status following hospital admission: secondary analysis of ICOD-R case–control data in Japan

Objectives To investigate the association between occupation and Parkinson’s disease (PD) risk and whether patients with PD change occupation after onset. Design A matched case–control study using ...