A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

The Gene Ontology (GO) is a collaborative effort that provides structured vocabularies for annotating the molecular function, biological role, and cellular location of gene products in a highly ...

The tool integrates de novo detection of NLR loci at the genome level with targeted genome reannotation, and systematically reconciles these results with existing annotations to produce a ...

Abstract: The rapid advancement of scRNA-seq has generated massive data for cell type annotation. However, current automated annotation methods remain limited: most approaches separately model either ...

Pygmy seahorses (Hippocampus bargibanti) evolved a mutualistic camouflaged association with gorgonian corals, mimicking its polyps and coloration. The genomic bases of several adaptations to their ...

Populating features table and first-order relations: 5000 features.... Populating features table and first-order relations: 1236000 features Populating features table and first-order relations: ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. It is an exciting time for researchers working to link proteins to their functions.

Comprehensive reference genomes have now been assembled for six ape species: siamang (a Southeast Asian gibbon), Sumatran orangutan, Bornean orangutan, gorilla, bonobo and chimpanzee. Areas of their ...

The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...

Prokaryotic genome assembly is the process of reconstructing a complete, accurate, and contiguous representation of a bacterium’s or archaeon’s DNA from fragmented sequencing data. This process is ...

Sedimentary ancient DNA (sedaDNA) provides valuable insights into past ecosystems, yet its functional diversity has remained unexplored due to potential limitations in gene annotation for short-read ...