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vanderbilt.edu
Oncogenic KRAS and BRAF Drive Metabolic Reprogramming in Colorectal Cancer.
Metabolic reprogramming, in which altered utilization of glucose and glutamine supports rapid growth, is a hallmark of most cancers. Mutations in the oncogenes KRAS and BRAF drive metabolic reprogramming through enhanced glucose uptake, but the broader impact of these mutations on pathways of carbon metabolism is unknown. Global shotgun ...
Aug 3, 2018
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